Symbol Name ID |
Lhx3
LIM homeobox protein 3 MGI:102673 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Decreased circulating ACTH concentration |
Decreased response to growth hormone stimulation test |
Ectopic posterior pituitary |
Anterior pituitary hypoplasia |
Ectopic anterior pituitary gland |
Hypopituitarism |
Abnormal prolactin level |
Pituitary hypothyroidism |
Absence of secondary sex characteristics |
Delayed puberty |
Hypogonadotropic hypogonadism |
Disease(s) Associated with LHX3 | |||||||||||
panhypopituitarism |
Mouse Phenotypes | endocrine/exocrine gland phenotype |
adrenal cortical hyperplasia |
abnormal pituitary gland morphology |
abnormal Rathke's pouch apoptosis |
abnormal Rathke's pouch development |
abnormal corticotroph morphology |
decreased gonadotroph cell number |
decreased lactotroph cell number |
absent lactotrophs |
absent somatotrophs |
absent thyrotrophs |
absent adenohypophysis |
adenohypophysis hypoplasia |
abnormal pituitary gland development |
absent pituitary intermediate lobe |
small pituitary intermediate lobe |
abnormal thyroid follicle morphology |
small prostate gland |
small seminal vesicle |
small testis |
decreased activity of thyroid gland |
abnormal sex gland secretion |
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Availability | Mouse Genotype | ||||||||||||||||||||||
Lhx3tm1(cre)Slp/Lhx3tm1(cre)Slp | |||||||||||||||||||||||
Lhx3tm1.1Sjr/Lhx3tm1.1Sjr | * | ||||||||||||||||||||||
Lhx3tm1Lmgd/Lhx3tm1Lmgd |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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